Donor Programme

Infertility means you cannot get pregnant (conceive). Primary Infertility refers to couple who have not become pregnant after at least 1 year having sex without using birth control methods.

About

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An embryo is formed with fertilization of an egg and a sperm.

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This treatment is needed in many conditions like :

  • Advanced age
  • Premature Ovarian failure or reproductive ageing
  • Decreasing ovarian reserve
  • Recurrent IVF failures due to poor oocyte quality
  • Risk of genetic disease transmission in offspring
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Even with ART treatment, women’s eggs are not capable of forming a healthy embryo which can give rise to pregnancy. In such conditions, donor egg is one of the treatment options offered.

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If above condition is associated with Azoospermia (sperms not retrieved surgically) or genetic abnormality in male partner, along with donor egg, donor sperm may also be used.

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If above condition is associated with Azoospermia (sperms not retrieved surgically) or genetic abnormality in male partner, along with donor egg, donor sperm may also be used.

Who are Egg Donors?

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Young women of age group of 20-30.

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Known fertility potential (Having their own genetically normal child within last 5 years).

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Not having any genetic disease or child affected with genetic disease.

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No history of recurrent miscarriage.

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No major medical or surgical illness.

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No addiction.

How is the Egg Donor selected and screened?

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Detailed case history and examination of donor is done :

  • Age/ Marital status/ Education/ Occupation
  • Menstrual and Obstetric history
  • Family history (history of any genetic/congenital abnormalities in any family member)
  • Personal history (habits like using tobacco, smoking, drinking, what is the contraceptive being used)
  • Detailed systemic examination
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Assessment of her Ovarian Reserve :

  • Donor’s ovarian reserve is assessed with her blood AMH (Anti-Mullerian Hormone level) and her AFC count (Antral follicle count) seen on Ultrasonography.
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Blood investigations to be done :

  • Routine tests- Hemogram and blood grouping
  • Infection screening- HIV, HBsAg, VDRL, HCV
  • Hormone profile- S.TSH
  • Hb Electrophoresis
  • Liver function test
  • Renal function test
  • Optional- Karyotyping
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After matching the requirements, the donor is recruited.

Procedure

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Matching with donor.

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Synchronization of menses of donor and recipient.

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Controlled ovarian hyperstimulation of donor.

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Recipient’s treatment to prepare the endometrium for implantation.

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Oocyte retrieval from the donor.

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In vitro Fertilization of retrieved oocytes with the recipient’s husband’s sperm /Donor sperm obtained from Sperm bank.

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Culture of embryos.

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Embryo transfer in recipient’s uterus and luteal phase support.

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Serum beta HCG level on day 14.

Success Rate

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As compared to the success rate of IVF with your own eggs, success rates with donor eggs and embryos are considerably high to the tune of 50-60%.

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There are no problems associated with pregnancy after oocyte or embryo donation.

Oocyte, Semen and Embryo freezing

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There are many couples or single individuals, who would wish to preserve their fertility potential (which decreases with age) and plan for family at a later stage.

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This could be people with professional or personal reasons. This could also be people unfortunately affected by cancer before finishing their reproductive life.

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These individuals could opt for semen or egg freezing or the couple could opt for embryo freezing (embryo is formed using wife’s egg and husband’s sperm).

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These freezing techniques provide time to the couples for accomplishing their desires and at the same time keeps the window of possibility open for them to become parents at a bit delayed stage of their life.

Still unsure? Talk to a Care Manager